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  1. T-bet activates Th1 genes through Mediator and the Super Elongation Complex. A Herweck et al. Cell Reports 2016, epub ahead of print. PMID: 27292648
  2.   T-bet as a key regulator of mucosal immunity. R Mohamed & GM Lord. Immunology 2016, 147, 367-376 PMID: 26726991
  3. Biomarkers of tolerance in kidney transplantation – are we predicting tolerance or response to immunosuppressive treatment. I Rebollo Mesa et al. American Journal of Transplantation 2016 in press.
  4. Altered CD40 and BCR signalling leads to increased IL-10 production in B-cells from tolerant kidney transplant patients. E Nova-Lamperti et al. Transplantation 2016 in press.
  5. Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index. A Hinney et al. Molecular Psychiatry 2016, epub ahead of print. PMID: 27184124
  6. Developing in vitro expanded CD45RA+ regulatory T cells as an adoptive cell therapy for Crohn’s disease. J Canavan et al. Gut 2016, 65, 584-594 PMID: 25715355
  7. IL-10-produced by human transitional B-cells down-regulates CD86 expression on B-cells leading to inhibition of CD4+ T-cell responses. E Nova-Lamperti et al. Nature Scientific Reports 2016, 6, 20044 PMID: 26795594     
  8. Markers of achievement for assessing and monitoring gender equity in translational research organisations: a rationale and study protocol. PV Ovseiko et al. BMJ Open 2016, 009022 PMID: 26743702
  9. Design and Implementation of the International Genetics & Translational Research in Transplantation Network (iGeneTRAIN). BJ Keating et al. Transplantation Sept 2015, epub ahead of print. PMID: 26479416
  10. Diversity of gut microflora is required for the generation of B cell with regulatory properties in a skin graft model. R Alhabbab et al. Nature Scientific Reports 2015, 5, 11554 PMID: 26109230    
  11.   Role of retinoic acid in the stability of the T-helper-type 1 lineage and implications for autoimmunity. C Brown et al. Lancet 2015, S25, 60340-60343 PMID: 26312847 
  12.   Immune Biomarkers: the promises and pitfalls of personalized medicine. JCD Willis and GM Lord. Nature Reviews in Immunology 2015, 15, 323-329 PMID: 25814400
  13. The unusual suspects - Innate lymphoid cells as novel therapeutic targets in IBD. R Goldberg et al. Nature Reviews Gastroenterology & Hepatology 2015, 12, 271-283 PMID: 25971811
  14. Preventing aristolochic acid nephropathy. N Anandagoda & GM Lord. Clinical Journal of the American society of Nephrology , 2015, 10(2) 167-8 PMID:25587104
  15. Interleukin-6 Increases Production of Cytokines by Colonic Innate Lymphoid Cells in Mice and Patients with Chronic Intestinal Inflammation. N Powell et al. Gastroenterology 2015, 149, 456-467 PMID: 25917784
  16. Retinoic acid signaling constrains the plasticity of Th1 cells and prevents development of pathogenic Th17 cells. C Brown et al. Immunity 2015, 42, 499-511 PMID: 25769610       
  17. Role and species-specific expression of colon T cell homing receptor GPR15 in colitis. LP Nguyen et al. Nature Immunology 2015, 16, 207-213 PMID: 25531831   
  18. CCR6-dependent positioning of memory B cells is essential for their ability to mount a recall response to antigen. R Elgueta et al. The Journal of Immunology 2015, 194, 505-513 PMID: 25505290       
  19. The transcription factor E4bp4/Nfil3 controls commitment to the NK lineage and directly regulates Eomes and Id2 expression. V Male et al. The Journal of Experimental Medicine 2014, 211, 635-642 PMID: 24663216      
  20. Using ancestry-informative markers to identify fine structure across 15 populations of European origin. WTCCC3. European Journal of Human Genetics. 2014, 22, 1190-1200 PMID: 24549058
  21. How might a diagnostic microRNA signature be used to speed up the diagnosis of sepsis? M Shankar-Hari & GM Lord. Expert Rev Mol Diagn 2014, 14, 249-251 PMID: 24649814     
  22. The immune cell transcription factor T-bet: a novel metabolic regulator. E Stolarczyk, GM Lord, JK Howard. Adipocyte 2014, 3, 58-62 PMID: 24575371      
  23. A genome-wide association study of anorexia nervosa. WTCCC3. Molecular Psychiatry 2014, 19, 1085-1094 PMID: 24514567 
  24. Genome-wide regulatory analysis reveals T-bet controls Th17 lineage differentiation through direct suppression of IRF4. MR Gökmen et al. The Journal of Immunology 2013, 191, 5925-5932 PMID: 24249732  
  25. Genome-wide sequencing of cellular microRNAs identifies a combinatorial expression signature diagnostic of sepsis. Y Ma et al. PLOS ONE 2013, 8, e75918 PMID: 24146790     
  26. Integration of lyoplate based flow cytometry and computational analysis for standardized immunological biomarker discovery. F Villanova et al. PLOS ONE 2013, 8, e65485 PMID: 23843942
  27.   Comparison of regulatory T cells in hemodialysis patients and healthy controls: Implications for cell-therapy in transplantation. B Afzali et al. Clinical Journal of the American Society of Nephrology 2013, 8, 1396-1405 PMID: 23580782    
  28. The rationale and benefits of stratifying patients for trials in immunotherapy, using inflammatory bowel disease (IBD) as an example. P Biancheri et alTrends in Immunology 2013, 34, 564-571 PMID: 24035478         
  29. The epidemiology, diagnosis and management of Aristolochic Acid Nephropathy. MR Gökmen et al. Annals of Internal Medicine 2013, 158, 469-477 PMID: 23552405    
  30. Improved insulin sensitivity despite increased visceral adiposity in mice deficient for the immune cell transcription factor T-bet. E Stolarczyk et al. Cell Metabolism 2013, 17, 520-533 PMID: 23562076
  31. Assessment of regulatory T cell function in forthcoming clinical trials of cell therapy. JB Canavan et alExpert Rev Mol Diagn 2013, 13, 5-7 PMID: 23256698       
  32. T-bet: a bridge between innate and adaptive immunity. V Lazarevic, LH Glimcher & GM Lord. Nature Reviews in Immunology 2013, 13, 777-789 PMID: 24113868  
  33. T-bet and GATA3 orchestrate Th1 and Th2 differentiation through lineage-specific targeting of distal regulatory elements. A Kanhere et al. Nature Communications 2012, 3:1268 PMID: 23232398       
  34. The transcription factor T-bet regulates intestinal inflammation mediated by interleukin-7 receptor+ innate lymphoid cells. N Powell et al. Immunity 2012, 37, 1-11 PMID: 23063332   
  35. Helicobacter pylori induces in vivo expansion of human regulatory T cells through stimulating IL-1? production by dendritic cells. PJ Mitchell et al. Clinical and Experimental Immunology 2012, 170, 300-309 PMID: 23121671        
  36. Dense fine-mapping study identifies new susceptibility loci for primary biliary cirrhosis. JZ Liu et al. Nature Genetics 2012, 44, 1137-1141 PMID: 22961000
  37. Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations. Y Okada et al. Nature Genetics 2012, 44, 904-909 PMID: 22797727     
  38. Aristolochic acid nephropathy. MR Gökmen & GM Lord. British Medical Journal 2012, 345, 9 PMID: 22705815    
  39. A rapid diagnostic test for regulatory T cell function to enable regulatory T cell therapy. J Canavan et al. Blood 2012, 119, 57-66 PMID: 22219224
  40. Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. International Consortium for Blood Pressure Genome-Wide Association Studies. Nature 2011, 478, 103-109 PMID: 21909115
  41. Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. LV Wain et al. Nature Genetics 2011, 43, 1005-1011 PMID: 21909110   
  42. Molecular genetic characterisation of SMAD signalling molecules in pulmonary artery hypertension. M Talat Nasim et al. Human Mutation 2011, 32, 1385-1389 PMID: 21898662
  43. An imaging flow cytometric method for measuring cell division history and molecular symmetry during mitosis. A Filby et al. Cytometry A 2011, 79, 496-506 PMID: 21638766  
  44. Transcriptional control of natural killer cell differentiation and function. A Martin-Fontecha, GM Lord, HJM Brady. Cell and Molecular Life Sciences 2011, 68, 3495-3503 PMID: 21863375     
  45. Relative resistance of human CD4+ memory T cells to suppression by CD4+CD25+ regulatory T cells. Afzali B et al. American Journal of Transplantation 2011, 11, 1734-1742 PMID: 21749646  
  46. Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis. Mells GF et al. Nature Genetics 2011, 43, 329-332 PMID: 21399635      
  47. Monocytes control natural killer cell differentiation to effector phenotypes. K Soderquest et al. Blood 2011, 117, 4511-4518 PMID: 21389319
  48. Cutting Edge: CD8+ T cell priming in the absence of natural killer cells leads to enhanced memory responses. K Soderquest et al. Journal of Immunology 2011, 186, 3304-3308   PMID: 21307295     
  49. Gene expression changes induced by the human carcinogen aristolochic acid I in renal and hepatic tissue of mice. VM Arlt et al. International Journal of Cancer 2011, 128, 21-32 PMID: 20232387
  50. Strategies for Translational Research in the United Kingdom. K Soderquest & GM Lord. Science Translational Medicine 2010, 35, 48-53 PMID: 20944087   
  51. Translational mini-review series on Th17 cells: development of mouse and human Th17 cellsE de Jong, T Suddason & GM LordClinical and Experimental Immunology 2010, 159, 148-158 PMID: 19912248          
  52. Complement regulator CD46 promotes immunoregulation by distinct effects on conventional and unconventional human T cells. J Cardone et al. Nature Immunology 2010, 11, 862-871 PMID: 2069 4009    
  53. Development of cross-platform biomarker signature to detect renal transplant tolerance in humans.  Sagoo P et alJournal of Clinical Investigation 2010, 120,1848-1861 PMID: 20501943 
  54. Transcriptional regulation of the mucosal immune system mediated by T-bet. N Powell et alMucosal Immunology 2010, 3, 567-577 PMID: 20844482       
  55. Genetic loci influencing kidney function and chronic kidney disease. JC Chambers et al. Nature Genetics 2010, 42, 373-375 PMID: 20383145
  56. T-bet, a Th1 transcription factor regulates the expression of Tim-3. GM Lord* et al. European Journal of Immunology, 2010, 40, 859-866 (*= equal & listed alphabetically) PMID: 20049876    
  57. The transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genes. RG Jenner et al. Proceedings of the National Academy of Sciences (USA) 2009, 106, 17876-17881 PMID: 19805038
  58. Colitis-associated colorectal cancer driven by T-bet deficiency in dendritic cells. WS Garrett et al. Cancer Cell 2009, 16, 208-219 PMID: 19732721
  59. Relative role of Th1 and Th17 effector cells in allograft rejection. K Atalar et al. Current Opinion in Organ Transplantation 2009, 14, 23-32 PMID: 19337142
  60. A central role for monocytes in TLR-mediated activation of the vasculature. JR Ward et al. Immunology 2009, 128, 58-68 PMID: 19689736      
  61. In vivo activated monocytes from the site of inflammation in humans specifically promote Th17 responses. HG Evans et al. Proceedings of the National Academy of Sciences (USA) 2009, 106, 6232-6237 PMID: 19325128
  62. Translational Medicine and the NIHR Biomedical Research Centre Concept. K Snape, RC Trembath & GM Lord. Quarterly Journal of Medicine 2008, 101, 901-906 PMID: 18689427   
  63. Optimal induction of Th17 cells in humans requires TCR ligation in the context of TLR-activated monocytes. HG Evans et al. Proceedings of the National Academy of Sciences (USA) 2007, 104, 17034-17039 PMID: 17942669       
  64. Communicable ulcerative colitis induced by T-bet deficiency in the innate immune system. GM Lord*+ et al. Cell 2007, 131, 33-45 (*= equal & listed alphabetically, +=corresponding author) PMID: 17923086  
  65. A Strategy for Translation. GM Lord+ & RC Trembath. The Lancet 2007, 369, 1771-1773 (+=corresponding author) PMID: 17531870   
  66. Absence of CC Chemokine Ligand 2 Does Not Limit Obesity-Associated Infiltration of Macrophages into Adipose Tissue. KE Inouye et al. Diabetes 2007, 56, 2242-2250 PMID: 17473219   
  67. Aristolochic acid mutagenesis: molecular clues to the aetiology of Balkan endemic nephropathy-associated urothelial cancer. VM Arlt et al. Carcinogenesis 2007, 28, 2253-2261 PMID: 17434925
  68. The role of T helper 17 (Th17) and regulatory T cells (Tregs) in human autoimmune diseases and transplantation. B Afzali et alClinical and Experimental Immunology 2007, 148, 32-46 PMID: 17328715      
  69. Dendritic cell expression of the transcription factor T-bet regulates mast cell progenitor homing to mucosal tissue. GM Lord* et al. The Journal of Experimental Medicine 2007, 205, 431-439 (* = equal & listed alphabetically) PMID: 17296784
  70. Leptin as a proinflammatory cytokine. GM Lord. Contributions to Nephrology 2006151, 151-164 PMID: 16929139            
  71. T-bet is required for optimal pro-inflammatory CD4+ T cell trafficking. GM Lord et al. Blood 2005, 106, 3432-3439 PMID: 16014561   
  72. DNA adducts and p53 mutations in a patient with aristolochic acid associated nephropathy. GM Lord+ et al. The American Journal of Kidney Diseases 2004, 43, 11-17 (+=corresponding author) PMID: 15042566
  73. Recent developments in the transcriptional regulation of cytolytic effector cells. LH Glimcher et alNature Reviews in Immunology 2004, 4, 900-911 PMID: 15516969     
  74. Leptin deficient mice are protected from accelerated nephrotoxic nephritis. RM Tarzi et al. American Journal of Pathology 2004, 164, 385-390 (+=corresponding author) PMID: 14742244     
  75.   Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine / metabolic dysfunction of human congenital leptin deficiency. IS Farooqi et al.  Journal of Clinical Investigation 2002, 110, 1093-1103 PMID: 12393845    
  76.   Leptin inhibits the anti-CD3 driven proliferation of peripheral blood T cells but enhances the production of pro-inflammatory cytokines. GM Lord et al. Journal of Leukocyte Biology 2002, 72, 330-338 PMID: 12149424      
  77. Leptin prevents the fall in plasma osteocalcin during starvation in male mice. AP Goldstone et al. Biochemical & Biophysical Research Communications 2002, 295, 475-481 PMID: 12150974
  78. Chinese herbal nephropathy. GM Lord+ and CD Pusey. The Lancet 2002, 359, 796-797 (+=corresponding author) PMID:11888616
  79. Balancing susceptibility to infection and autoimmunity: a role for leptin? G Matarese et alTrends in Immunology 2002, 23, 182-187 PMID: 11923112     
  80. Role of leptin in immunology.  GM Lord.  Nutrition Reviews 2002: 60, 35-38.  PMID: 12403082   
  81. Aristolochic acid as a causative factor in a case of Chinese herbal nephropathy. AJ Cronin et al. Nephrology Dialysis Transplantation 2002, 17, 524-525 (+=corresponding author) PMID: 11865112   
  82. Urothelial malignancy and Chinese herbal nephropathy. GM Lord+ et al. The Lancet 2001, 358, 1515-1516 (+=corresponding author) PMID: 11705569  
  83. The bioenergetics of the immune system. GM Lord+ et al. Science 2001, 292, 855-856 (+=corresponding author) PMID: 1134 1277    
  84. Leptin potentiates experimental autoimmune encephalomyelitis in SJL female mice and confers susceptibility to males. G Matarese et al. European Journal of Immunology 2001, 31, 1324-1332 PMID: 11465089
  85. Requirement for leptin in the induction and progression of autoimmune encephalomyelitis. G Matarese et al. Journal of Immunology 2001,166, 5909-5916 PMID: 11342605
  86. The peritoneal fluid concentration of leptin is increased in women with peritoneal but not ovarian endometriosis. G De Placido et al. Human Reproduction 2001, 16, 1251-1254 PMID: 11387300      
  87. Starvation, Leptin and Epithelial Cell Proliferation in the Gastrointestinal Tract of the Mouse. M Chaudhary et al. Digestion 2000, 61, 223-229 PMID: 10878448       
  88. Increased leptin levels in serum and peritoneal fluid of patients with pelvic endometriosis. G Matarese et al. Journal of Clinical Endocrinology and Metabolism 2000, 85, 2483-2487 PMID:  10902797  
  89. Leptin protects mice from starvation-induced lymphoid atrophy and increases thymic cellularity in ob/ob mice. GM Lord* et al. Journal of Clinical Investigation 1999, 104, 1051-1059 (*=equal & listed alphabetically) PMID: 10525043      
  90. Nephropathy caused by Chinese herbs in the UK. GM Lord+ et al. The Lancet 1999: 354, 481-482 (+=corresponding author) PMID: 10465175      
  91. A kinetic differentiation model for the action of altered TCR ligands. GM Lord et al. Immunology Today 1999, 20, 33?39 PMID: 10081228    
  92.  Immunotherapy. GM Lord. Journal of the Royal College of Physicians 1999, 33, 61?64 PMID: 10192073   
  93. Leptin modulates the T cell immune response and reverses starvation-induced immunosuppression. GM Lord et al. Nature 1998, 394, 897-901 PMID: 9732873     
  94. Plasma immunoreactive leptin concentration in end-stage renal disease. GM Lord* et al. Clinical Science 1997, 93, 119-126 (*=equal & listed alphabetically) PMID: 9301426   
  95. Multiple cladosporium brain abscesses in a renal transplant patient - aggressive management improves outcome. AD Salama et al. Transplantation 1997, 63, 160-162 PMID: 9000680     
  96. Diabetes and rhabdomyolysis. GM Lord. The British Medical Journal 1993, 307, 1126-1129 PMID: 8251814    
  97.   Spontaneous spinal epidural haematoma - A cautionary tale. GM Lord & N Mendoza. The Archives of Emergency Medicine 1993, 10, 339-340 PMID: 8110329      

Book Chapters

 

1.       Aristolochic acid nephropathy. MR Gökmen & GM Lord. The Oxford Textbook of Clinical Nephrology 2015

2.       The commensal microbiota and its relationship to homeostasis and disease. N Powell et al. In Principles of Mucosal Immunology 2011. Eds: PD Smith, TT Macdonald, RS Blumberg

3.       Genome Wide Polymorphism association analysis in organ transplantation. E Perucha, MP Hernandez-Fuentes & GM Lord. Ed Drug Pharma 2010, ISBN 978-984

4.       The role of leptin in sepsis. PA Glynne, M Singer, GM Lord. In Vincent JL (ed.). Yearbook of Intensive Care and Emergency Medicine. Berlin, Springer-Verlag, 2004, 41-50

5.       Leptin: its role in immunomodulation and susceptibility to infection. GM Lord.  In Cytokines and chemokines in infectious diseases 2002. Eds: M Kotb and T Calandra

6.       Renovascular disease and cholesterol emboli. GM Lord. In Acute Renal Failure in Practice 2001. Eds: PA Glynne, AR Allen, CD Pusey

7.       The immune response to alloantigens. GM Lord & RI Lechler. In Allogeneic immunotherapy for malignant diseases 1998: ch. 2, pp 13-38. Eds: J Barrett & YZ Jiang; Pub: Marcel Dekker Inc, NY, USA

8.       The allogeneic immune response. GM Lord & RI Lechler. In Textbook of Immunology 1998. Ed: R Duquesnoy